Injectable hyaluronic acid (HA) biomaterials are currently applied in numerous biomedical areas and due to their widespread use, bacterial infections and painful inflammation are associated with post-injection health complications. In this article, i+Med successfully crosslinks HA hydrogels with 14-butanediol diglycidyl ether (BDDE) loaded with cefuroxime (CFX), tetracycline (TCN) and amoxicillin (AMX) antibiotics, and acetylsalicylic acid (ASA) anti-inflammatory agent to promote antibacterial and anti-inflammatory responses and thus, prevent the aforementioned post-injection complications.
Drug Delivery from Hyaluronic Acid–BDDE Injectable Hydrogels for Antibacterial and Anti-Inflammatory Applications
