Nanocarriers 2019-10-10T09:44:39+01:00

Nanocarriers

Encapsulation of compounds is a technique employed in medical, food, pharmaceutical and cosmetic industries. Carrier systems allow the controlled and targeted release of vectorised active compounds.

Benefits:

  • Protection of the compound (improved stability).

  • Better bioavailability.

  • Decreased toxicity.

  • Masking of undesired (tastes, smells…)

  • Increased solubility of insoluble compounds.

  • Controlled delivery.

  • Target delivery.

  • Increased efficacy.

  • More cost effective due to lower dosing levels and drug usage.

  • Improved patient compliance (lower number of administrations).

nanocarriers imasmed
nanocarriers imasmed biomédica

Spherical vesicles made of a double phospholipid layer, where the polar part is oriented towards de internal and external médium, making an internal polar layer and an intermediate apolar layer.

Vesicles with a liquid core that can be aqueous or non-aqueous, covered by a polymeric solid shell.

Solid polymeric matrix, where the drug is loaded into the polymer matrix or adsorbed on the surface.

Solid lipid nanoparticles (SLN) or nanostructured lipid nanoparticles (NLC)

-SLN: formed from triglycerides with saturated fatty acid chains

-NLC: formed from triglycerides with a mixture of saturated and unsaturated fatty acid chains.

They are formed by hydrophilic and hydrophobic polymeric blocks that are arranged as micelles of different types as a function of the surrounding environment.