Encapsulation of compounds is a technique employed in medical, food, pharmaceutical and cosmetic industries. Carrier systems allow the controlled and targeted release of vectorised active compounds.
Protection of the compound (improved stability).
Masking of undesired (tastes, smells…)
Increased solubility of insoluble compounds.
More cost effective due to lower dosing levels and drug usage.
Improved patient compliance (lower number of administrations).
Administering drugs to hard-to-reach areas such as joints, the inner eye or ear.
Our experience in the encapsulation of compounds allow us to develop different types of nanocarriers in order to select the optimal system for desired application.
I+Med offers customized nanoencapsulation services and other related services such as delivery studies, surface modification and conjugation, among others.
The nanocarrier systems can be incorporated into coatings, implants, injectable solutions, creams, etc.
Spherical vesicles made of a double phospholipid layer, where the polar part is oriented towards de internal and external médium, making an internal polar layer and an intermediate apolar layer.
Vesicles with a liquid core that can be aqueous or non-aqueous, covered by a polymeric solid shell.
Solid polymeric matrix, where the drug is loaded into the polymer matrix or adsorbed on the surface.
Solid lipid nanoparticles (SLN) or nanostructured lipid nanoparticles (NLC)
-SLN: formed from triglycerides with saturated fatty acid chains
-NLC: formed from triglycerides with a mixture of saturated and unsaturated fatty acid chains.
They are formed by hydrophilic and hydrophobic polymeric blocks that are arranged as micelles of different types as a function of the surrounding environment.