Project Description


TrHCROSS is a biocompatible hydrogel of crosslinked sodium hyaluronate obtained by biofermentation and highly purified, dissolved in a physiological and isotonic buffer. The product is an injectable hydrogel, sterile and apyrogenic, with a low level of endotoxins.

trhcross inyección intraarticular de ácido hialurónico entrecruzado


TrHCROSS is intended to be injected intra-articularly in the synovial space of the knee as viscosupplementation medium for synovial fluid when its viscosity has been reduced due to osteoarthritis process in patients who have not responded adequately to conservative non-pharmacological therapy and simple analgesics.

Material / Composition

TrHCROSS contains high molecular weight crosslinked hyaluronic acid obtained by biofermentation of injectable grade and high purity, dissolved in a physiological buffer with pharmacopeia quality ingredients and water for injection (WFI).


Due to its rheological and physicochemical properties, TrHCROSS:

+ Reduces the pain and increases the functionality of the affected joint.

+ Provides a lubricant and shock-absortion effect on the affected join.

+ Improves the quality of life of the patient.

Technical specifications

+ Visual appearance: clear liquid
+ Physiological pH
+ Isotonic
+ Endotoxin content <0.2EU/mL
+ Sterile product
+ Biocompatible product


TrHCROSS is supplied in a pre-filled syringe of 4,4mL, ready to use.